Pharmaceuticals & Drug Delivery Systems | packaging testing blog cover image
Pharma & Medical Devices
2025-09-05

Pharmaceuticals & Drug Delivery Systems

The Criticality of Gliding Force

Prefilled Syringes (PFS) require a delicate balance: the plunger must move smoothly without leakage.

- The Risk: If the "Break-loose Force" is too high, the needle may jerk during injection, causing patient pain. If the "Gliding Force" is inconsistent, the dosage accuracy is compromised.

KHT MED Series: The Compliance Expert

KHT provides the definitive solution for USP <1104> and ChP 2025 (General Chapter 4015).

- Solution: The KHT MED-01 features a specialized "Syringe Test Mode" that records force data in real-time. It uses a high-precision 50N sensor to capture the minute force fluctuations (Break-loose vs. Sustained) that generic industrial testers miss.

- New Standard (ChP 4043): We also support the new "Adaptor Cap Pull-out Force" test, offering the specialized fixture and 20mm/min speed control required by the 2025 Pharmacopoeia.

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About Author
Amy Gu | packaging testing engineer and author
Amy Gu
Amy Gu is a Senior Technical Specialist and Product Manager at KHT, with over 8 years of expertise in material mechanics and pharmaceutical packaging validation. Specializing in 'High-Precision Low-Force Testing' and 'Film Property Analysis', Amy possesses deep knowledge of global compliance standards including ChP 2025 (General Chapters 4008, 4015, 4043), USP <1104>, and ASTM D882. She has successfully guided global laboratories in upgrading from basic tensile testing machines to advanced KHT MED Series systems, enabling precise verification of Syringe Gliding Forces and Rubber Stopper Puncture resistance. Her technical leadership focuses on solving the 'Data Integrity' gap in QC labs, advising on critical parameter settings (such as 300mm/min for Heat Seal or 20mm/min for Adaptor Pull-out). Amy is committed to delivering factory-direct, audit-ready testing solutions that ensure your products survive the rigorous global supply chain.

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